Substances starting with R
Every substance in the newest version of the EU reference dates list that starts with R, with how often a PSUR is due. Open one for its data lock points and submission dates.
91 substances
- rabeprazoleevery 5 years
- rabies vaccineevery 5 years
- racecadotrilevery 5 years
- rADAMTS13every 1 year
- radium-223 dichlorideevery 3 years
- raloxifeneevery 5 years
- raltegravirevery 3 years
- raltitrexedevery 8 years
- ramiprilevery 6 years
- ramipril / bisoprololevery 7 years
- ramucirumabevery 3 years
- ranibizumabevery 3 years
- ranibizumab (Susvimo)every 6 months
- ranitidineevery 5 years
- ranolazineevery 3 years
- rasagilineevery 5 years
- rasburicaseevery 5 years
- ravulizumabevery 3 years
- rdESAT-6 / rCFP-10every 6 months
- reboxetineevery 5 years
- recombinant vesicular stomatitis virus - zaire ebolavirus vaccine (live)every 3 years
- regadenosonevery 3 years
- regorafenibevery 3 years
- relugolixevery 1 year
- relugolix / estradiol / norethisterone acetateevery 3 years
- remdesivir (Veklury)every 3 years
- remibrutinibevery 6 months
- remifentanilevery 5 years
- remimazolamevery 1 year
- repaglinideevery 5 years
- repotrectinibevery 6 months
- reslizumabevery 3 years
- resmetiromevery 6 months
- resorcinolevery 10 years
- respiratory Syncytial Virus (RSV) vaccine (recombinant, adjuvanted)every 1 year
- respiratory syncytial virus mRNA vaccineevery 6 months
- respiratory syncytial virus vaccine (bivalent, recombinant)every 1 year
- retifanlimabevery 6 months
- retinolevery 9 years
- rezafunginevery 1 year
- rhubarb extract / salicylic acidevery 15 years
- ribavirin (oral formulations)every 3 years
- ribociclibevery 3 years
- riboflavinevery 10 years
- rifabutinevery 11 years
- rifampicinevery 5 years
- rifamycinevery 11 years
- rifaximinevery 8 years
- rilmenidineevery 5 years
- rilpivirine (for intramuscular use)every 3 years
- rilpivirine (for oral use)every 3 years
- riluzoleevery 5 years
- rilzabrutinibevery 6 months
- rimegepantevery 1 year
- riociguatevery 3 years
- ripretinibevery 1 year
- risankizumabevery 5 years
- risdiplamevery 1 year
- risedronate, risedronate / calcium / colecalciferolevery 5 years
- risperidoneevery 5 years
- ritlecitinibevery 1 year
- ritodrine hydrochlorideevery 8 years
- ritonavirevery 5 years
- rituximabevery 3 years
- rivaroxaban, acetylsalicylic acid / rivaroxabanevery 3 years
- rivastigmineevery 5 years
- rizatriptanevery 5 years
- rocuroniumevery 5 years
- roflumilastevery 5 years
- romiplostimevery 5 years
- romosozumabevery 3 years
- ropeginterferon alfa-2bevery 3 years
- ropiniroleevery 3 years
- ropivacaineevery 5 years
- rosuvastatinevery 5 years
- Rosuvastatin/ Omega-3-acid ethyl estersevery 5 years
- rotavirus vaccine monovalent (live, oral)every 3 years
- rotavirus vaccine pentavalent (live, oral)every 3 years
- rotigotineevery 5 years
- roxadustatevery 1 year
- roxithromycinevery 3 years
- rozanolixizumabevery 1 year
- rubidium (82Rb) chlorideevery 3 years
- rucaparibevery 2 years
- rufinamideevery 5 years
- rupatadineevery 5 years
- rurioctocog alfa pegolevery 3 years
- ruscogenin / trimebutineevery 10 years
- rutosideevery 10 years
- ruxolitinibevery 1 year
- ruxolitinib (for non-segmental vitiligo)every 1 year
Source: European Medicines Agency, list of EU reference dates and frequency of submission of periodic safety update reports, EMA/630645/2012 Rev.165, published 21 Oct 2026.