Substances starting with T
Every substance in the newest version of the EU reference dates list that starts with T, with how often a PSUR is due. Open one for its data lock points and submission dates.
216 substances
- tabelecleucelevery 1 year
- tacalcitolevery 8 years
- tacrolimus (systemic formulations)every 3 years
- tacrolimus (topical formulations)every 3 years
- tadalafilevery 3 years
- tafamidisevery 2 years
- tafasitamabevery 6 months
- tafluprostevery 3 years
- tafluprost / timololevery 3 years
- tagraxofuspevery 3 years
- talazoparibevery 3 years
- talimogene laherparepvecevery 3 years
- talquetamabevery 6 months
- tamoxifenevery 5 years
- tamsulosinevery 5 years
- tapentadolevery 5 years
- tarlatamabevery 6 months
- tasimelteonevery 3 years
- tasonerminevery 7 years
- tauroselcholic [75Se] acidevery 5 years
- tebentafuspevery 1 year
- technetium (99mtc) 3,3-diphosphono-1,2-propanedicarboxylic acidevery 15 years
- technetium (99mtc) albumin nanocolloidevery 15 years
- technetium (99mTc) bicisateevery 15 years
- technetium (99mtc) depreotideevery 15 years
- technetium (99mTc) edda / hynic-octreotideevery 15 years
- technetium (99mTc) exametazimeevery 15 years
- technetium (99mtc) human albuminevery 15 years
- technetium (99mtc) macrosalbevery 15 years
- technetium (99mtc) mebrofeninevery 15 years
- technetium (99mtc) medronic acidevery 15 years
- technetium (99mTc) mertiatide, technetium (99mTc) betiatideevery 15 years
- technetium (99mtc) N,N'-ethylene-(L,L)-dicysteineevery 15 years
- technetium (99mtc) pentetateevery 15 years
- technetium (99mTc) pertechnetateevery 15 years
- technetium (99mtc) sestamibievery 15 years
- technetium (99mTc) succimerevery 15 years
- technetium (99mTc) tetrofosmin, tetrofosminevery 15 years
- technetium (99mTc) tin colloidevery 15 years
- technetium (99mTc) trimethylphenylcarbamoylmethyliminodiacetic acidevery 15 years
- teclistamabevery 1 year
- tecovirimatevery 1 year
- tedizolid phosphateevery 3 years
- teduglutideevery 2 years
- tegafurevery 8 years
- teicoplaninevery 5 years
- telmisartan / indapamideevery 5 years
- telotristatevery 3 years
- temazepamevery 9 years
- temocillinevery 9 years
- temoporfinevery 13 years
- temozolomideevery 3 years
- temsirolimusevery 5 years
- tenecteplaseevery 3 years
- teniposideevery 9 years
- tenofovir alafenamideevery 3 years
- tenofovir disoproxilevery 3 years
- tenonitrozoleevery 13 years
- tenoxicamevery 5 years
- teplizumabevery 6 months
- tepotinibevery 1 year
- teprotumumabevery 6 months
- terazosinevery 8 years
- terbinafineevery 3 years
- terbutalineevery 5 years
- teriflunomideevery 3 years
- teriparatideevery 3 years
- terizidoneevery 5 years
- terlipressinevery 3 years
- tertatololevery 9 years
- testosterone (all formulations apart from topical use)every 3 years
- testosterone (topical use)every 3 years
- tetanus vaccinesevery 5 years
- tetrabenazineevery 5 years
- tetracaineevery 9 years
- tetracosactideevery 9 years
- tetracyclineevery 10 years
- tetracycline (topical use)every 9 years
- tetryzolineevery 10 years
- tezacaftor / ivacaftorevery 3 years
- tezepelumabevery 1 year
- thalidomideevery 3 years
- thallium [201TL]every 10 years
- theophyllineevery 5 years
- thiamazoleevery 8 years
- thiamineevery 9 years
- thiamine / cyanocobalamine / riboflavin / pyridoxineevery 3 years
- thiamine / riboflavin/ pyridoxine / ascorbic acid / nicotinamide / glucose, thiamine / riboflavin / pyridoxine / ascorbic acid / nicotinamide, ascorbic acid / biotin / cyanocobalamin / folic acid / nicotinamide / pantothenic acid / pyridoxine hydrochloride / riboflavin / thiamine, riboflavin / thiamine / calcium folinate / cyanocobalamin / nicotinamide, calcium pantothenate / nicotinamide / pyridoxine / riboflavin / thiamine, dexpanthenol / nicotinamide / pyridoxine / riboflavin / thiamine, biotin / calcium pantothenate / cyanocobalamin / nicotinamide / pyridoxine / riboflavin / thiamineevery 10 years
- thiamphenicolevery 5 years
- thiamphenicol glycinate acetylcysteinateevery 10 years
- thiocolchicoside, paracetamol / thiocolchicosideevery 3 years
- thioctic acidevery 8 years
- thiopentalevery 15 years
- thioridazineevery 9 years
- thiotepaevery 3 years
- thyrotropin alfaevery 5 years
- tiagabineevery 5 years
- tianeptineevery 5 years
- tiaprideevery 3 years
- tiaprofenic acidevery 9 years
- tibezonium iodideevery 10 years
- tiboloneevery 5 years
- ticagrelor, acetylsalicylic acid / ticagrelorevery 3 years
- tick-borne encephalitis vaccine (inactivated)every 3 years
- ticlopidineevery 8 years
- tigecyclineevery 5 years
- tilactaseevery 9 years
- tilbroquinol / tiliquinolevery 10 years
- tildrakizumabevery 1 year
- tilidineevery 9 years
- timolol (eye preparations)every 5 years
- timolol (systemic use)every 7 years
- timolol / travoprostevery 5 years
- tinidazole, nystatin / tinidazoleevery 10 years
- tinzaparinevery 7 years
- tioconazole, tioconazole / hydrocortisoneevery 13 years
- tioguanineevery 9 years
- tiotropiumevery 5 years
- tipranavirevery 5 years
- tiratricolevery 6 months
- tirbanibulinevery 1 year
- tirofibanevery 5 years
- tiropramideevery 9 years
- tirzepatideevery 1 year
- tisagenlecleucelevery 1 year
- tislelizumabevery 3 years
- tisotumab vedotinevery 6 months
- tivozanibevery 3 years
- tixocortol, chlorhexidine gluconate / tixocortol pivalateevery 5 years
- tizanidineevery 5 years
- tobramycin (inhalation powder, capsules)every 6 years
- tobramycin (nebuliser solution) (apart from centrally authorised product)every 3 years
- tobramycin (nebuliser solution) (centrally authorised product only)every 3 years
- tobramycin (ophthalmic and otic use)every 5 years
- tobramycin (systemic use)every 8 years
- tocilizumabevery 3 years
- tocofersolanevery 1 year
- tofacitinibevery 3 years
- tofersenevery 1 year
- tofisopamevery 7 years
- tolbutamideevery 10 years
- tolcaponeevery 3 years
- tolebrutinibevery 6 months
- tolfenamic acidevery 8 years
- tolnaftateevery 9 years
- tolnaftate / triclosanevery 9 years
- tolperisoneevery 3 years
- tolterodineevery 5 years
- tolvaptan (indicated for adults with autosomal dominant polycystic kidney disease (ADPKD))every 3 years
- tolvaptan (indicated for adults with hyponatraemia secondary to syndrome of inappropriate antidiuretic hormone secretion (SIADH))every 3 years
- topiramateevery 5 years
- topotecanevery 5 years
- torasemideevery 8 years
- toremifeneevery 5 years
- toripalimabevery 1 year
- tosylchloramideevery 8 years
- tovorafenibevery 6 months
- trabectedinevery 3 years
- tralokinumabevery 1 year
- tramadolevery 3 years
- tramazolineevery 11 years
- trametinibevery 3 years
- trandolapril, verapamil / trandolaprilevery 8 years
- tranexamic acidevery 8 years
- transfer factor porcineevery 9 years
- tranylcypromineevery 8 years
- trastuzumabevery 3 years
- trastuzumab deruxtecanevery 6 months
- trastuzumab emtansineevery 2 years
- travoprostevery 5 years
- trazodoneevery 6 years
- tremelimumabevery 1 year
- trenibotulinumtoxinEevery 6 months
- treosulfan (except for centrally authorised product)every 5 years
- treosulfan (for centrally authorised product)every 3 years
- treprostinilevery 3 years
- tretinoin (oral formulations)every 5 years
- tretinoin (topical formulations)every 5 years
- triamcinolone (intraocular formulations)every 3 years
- triamcinolone (tablets and injectables)every 8 years
- triamcinolone (topical and nasal formulations)every 5 years
- triamcinolone / lidocaine (rectal use)every 9 years
- triamtereneevery 10 years
- triamterene / trichlormethiazideevery 9 years
- triazolamevery 5 years
- tribenosideevery 10 years
- triclocarbanevery 9 years
- triclosanevery 9 years
- trientineevery 3 years
- trifaroteneevery 3 years
- trifluperidolevery 11 years
- trifluridine / tipiracilevery 3 years
- triflusalevery 9 years
- triglyceride combinations (e.g. olive oil, soya bean oil, fish oil)/ with or without mineral compounds/electrolytes (i.v. application)every 5 years
- trihexyphenidylevery 11 years
- trimebutineevery 9 years
- trimecaineevery 9 years
- trimetazidineevery 3 years
- trimethoprimevery 7 years
- trimipramineevery 11 years
- tripelennamineevery 10 years
- triptorelinevery 5 years
- trofinetideevery 6 months
- trolamineevery 9 years
- tromantadineevery 9 years
- tropicamideevery 10 years
- trospiumevery 9 years
- troxerutin, troxerutin / heptaminol / ginkgo leafevery 8 years
- tryptophanevery 8 years
- tuberculin purified protein derivativeevery 7 years
- tucatinibevery 1 year
- turoctocog alfaevery 3 years
- turoctocog alfa pegolevery 3 years
- typhoid polysaccharide vaccineevery 3 years
- typhoid vaccine (live, attenuated)every 3 years
- tyrothricinevery 11 years
Source: European Medicines Agency, list of EU reference dates and frequency of submission of periodic safety update reports, EMA/630645/2012 Rev.165, published 21 Oct 2026.