Substances starting with B
Every substance in the newest version of the EU reference dates list that starts with B, with how often a PSUR is due. Open one for its data lock points and submission dates.
188 substances
- bacampicillinevery 9 years
- bacillus clausii multi-antibioresistant sporesevery 5 years
- bacitracin, bacitracin / neomycin, bacitracin / polymyxin, bacitracin / neomycin / polymyxin, bacitracin / hydrocortisone / neomyicin, bacitracin zinc / cysteine / glycine / neomycin/ threonineevery 9 years
- baclofen (intrathecal use)every 5 years
- baclofen (oral use, for muscle spasticity indication)every 3 years
- bacterial lysate of haemophilus influenzae / klebsiella pneumoniae / moraxella catarrhalis / staphylococcus aureus / streptococcus mitis / streptococcus pneumoniae / streptococcus pyogenes, bacterial lysate of haemophilus influenzae / klebsiella pneumoniae / moraxella catarrhalis / staphylococcus aureus / streptococcus pneumoniae / streptococcus pyogenes, streptococcus pneumoniae / streptococcus agalactiae / staphylococcus aureus / haemophilus influenzaeevery 5 years
- baloxavir marboxilevery 3 years
- balsalazideevery 7 years
- bambuterolevery 5 years
- bamifyllineevery 9 years
- bamipineevery 10 years
- baricitinibevery 1 year
- barium sulphate, barium sulphate combinationsevery 28 years
- barnidipineevery 7 years
- basiliximabevery 3 years
- bazedoxifeneevery 10 years
- BCG (bacillus calmette-guérin) for Immunotherapyevery 5 years
- BCG vaccine (freeze-dried)every 5 years
- beclometasoneevery 5 years
- beclometasone / formoterol (inhalative application)every 5 years
- beclometasone / formoterol / glycopyrronium bromideevery 1 year
- beclometasone / salbutamolevery 5 years
- beclometasone dipropionate / neomycin sulfateevery 11 years
- bedaquilineevery 3 years
- belantamab mafodotinevery 6 months
- belataceptevery 5 years
- belimumabevery 3 years
- belladonna alkaloids / caffeine / ergotamine tartrate / paracetamolevery 9 years
- belladonna alkaloids / ergotamine tartrate / phenobarbitalevery 9 years
- belladonna extract / hyosciamine / papaverine hydrochlorideevery 9 years
- belumosudilevery 6 months
- belzutifanevery 6 months
- bemiparinevery 5 years
- bemotrizinol / butyl methoxydibenzoylmethane / drometrizoleevery 9 years
- bempedoic acid, bempedoic acid / ezetimibeevery 3 years
- benazeprilevery 5 years
- benazepril / hydrochlorothiazideevery 5 years
- bencyclaneevery 13 years
- bendamustine hydrochlorideevery 5 years
- bendazacevery 10 years
- bendroflumethiazide, bendroflumethiazide / potassium chlorideevery 6 years
- benfotiamineevery 5 years
- benfotiamine / glutamate sodium / inositolevery 9 years
- benperidolevery 6 years
- benralizumabevery 3 years
- benserazide / levodopaevery 5 years
- bentazepamevery 9 years
- benzalkonium (exluding vaginal use), benzalkonium chloride / hexylresorcinolevery 7 years
- benzalkonium / benzocaine / tyrothricinevery 8 years
- benzalkonium / chloride solution / light liquid paraffin / triclosanevery 9 years
- benzalkonium / ethyl alcoholevery 7 years
- benzalkonium chloride / cetrimide, cetrimide / dimeticoneevery 9 years
- benzalkonium chloride / chlorhexidine digluconateevery 7 years
- benzalkonium chloride / dequalinium chlorideevery 9 years
- benzalkonium chloride / isopropyl myristate / paraffin liquid, benzalkonium chloride / chlorhexidine / isopropyl myristate / paraffin liquidevery 8 years
- benzbromaroneevery 9 years
- benzocaineevery 18 years
- benzocaine / cetylpyridinium chloride / dichlorobenzyl alcohol / gramicidinevery 8 years
- benzocaine / chlorhexidine, benzocaine / chlorhexidine / tyrothricinevery 18 years
- benzocaine / chloroxylenolevery 18 years
- benzocaine / dequalinium chloride / dexamethasone / tyrothricinevery 9 years
- benzocaine / dequalinium hydrochlorideevery 18 years
- benzocaine / hamamelis water / racephedrine hydrochlorideevery 18 years
- benzocaine / hydrocortisone acetateevery 9 years
- benzocaine / menthol / phenol, racemic / thymolevery 18 years
- benzocaine / phenazoneevery 18 years
- benzocaine / triclosanevery 18 years
- benzododecinium / boric acidevery 11 years
- benzoxonium chloride / lidocaine hydrochlorideevery 9 years
- benzoyl peroxideevery 10 years
- benzoyl peroxide / clindamycin phosphateevery 8 years
- benzoyl peroxide / erythromycinevery 9 years
- benzoyl peroxide hydrous / potassium hydroxyquinoline sulphateevery 13 years
- benzydamineevery 5 years
- benzydamine / cetylpyridineevery 7 years
- benzyl alcohol / ethanol / isopropyl alcohol (covers other synonymous terms such as 2-propanol)every 7 years
- benzyl benzoate / disulfiramevery 9 years
- benzyl nicotinate / camphor / dimethyl sulfoxide / nonivamide / turpentine oil, Nicoboxil/ Nonivamideevery 5 years
- benzyl nicotinate / etofenamateevery 8 years
- benzyl nicotinate / heparin sodiumevery 8 years
- benzylbenzoateevery 18 years
- benzylnicotinateevery 18 years
- benzylpenicillin, benzathine benzylpenicillin, benzathine benzylpenicillin / lidocaine, procaine benzylpenicillin, benzathine benzylpenicillin / procaine benzylpenicillinevery 5 years
- beremagene geperpavecevery 6 months
- berotralstatevery 3 years
- besilesomabevery 5 years
- beta-alanineevery 5 years
- beta-caroteneevery 9 years
- betahistineevery 3 years
- betaine anhydrous (centrally authorised product only)every 3 years
- betamethasoneevery 9 years
- betamethasone / chloramphenicolevery 18 years
- betamethasone / gentamicinevery 9 years
- betamethasone / tetryzolineevery 9 years
- betamethasone dipropionate / calcipotriolevery 9 years
- betamethasone dipropionate / clotrimazoleevery 9 years
- betamethasone dipropionate / clotrimazole / gentamicinevery 9 years
- betamethasone dipropionate / salicylic acidevery 9 years
- betamethasone sodium phosphate / neomycin sulfateevery 9 years
- betamethasone valerate / clioquinolevery 9 years
- betamethasone valerate / fusidic acidevery 9 years
- betaxololevery 5 years
- bethanecholevery 5 years
- bevacizumabevery 3 years
- bevacizumab gammaevery 1 year
- bexaroteneevery 3 years
- bezafibrateevery 7 years
- bibrocatholevery 7 years
- bicalutamideevery 3 years
- biclotymolevery 7 years
- biclotymol / enoxolone / muramidase hydrochlorideevery 8 years
- bictegravir / emtricitabine / tenofovir alafenamideevery 3 years
- bifonazoleevery 8 years
- bifonazole / ureaevery 9 years
- bilastineevery 5 years
- bimatoprostevery 5 years
- bimatoprost / timololevery 5 years
- bimekizumabevery 3 years
- binimetinibevery 3 years
- biotinevery 7 years
- biperidenevery 3 years
- birch bark extract (centrally authorised products)every 1 year
- bisacodyl, bisacodyl / senna dry extract / senna pods / sennae folium, sennosides calcium salts, cassia angustifolia / cassia fistula, senna glycosidesevery 10 years
- bismuth / lidocaine / zinc oxide, lidocaine / zinc oxideevery 8 years
- bismuth salts and combinations (except for fixed dose combination bismuth subcitrate potassium / metronidazole / tetracycline)every 23 years
- bismuth subcitrate potassium / metronidazole / tetracyclineevery 3 years
- bismuth subgallate / charcoal activated / citric acidevery 7 years
- bismuth subgallate / fluocinolone acetonide / lidocaine / mentholevery 9 years
- bisoprololevery 6 years
- bisoprolol / hydrochlorothiazideevery 7 years
- bisoprolol / perindoprilevery 7 years
- bisulepinevery 7 years
- bivalirudinevery 5 years
- bleomycinevery 10 years
- blinatumomabevery 3 years
- borax / boric acidevery 23 years
- boric acid / calcium thiocyanate / camphor / menthol / methenamineevery 9 years
- boric acid / carbethopendecinium bromide / sodium tetraborateevery 11 years
- bornaprinevery 10 years
- bortezomibevery 3 years
- bosentanevery 3 years
- bosutinibevery 3 years
- botulinum neurotoxin type a (150 kd) free from complexing proteinsevery 3 years
- botulinum toxin a - haemagglutinin complexevery 3 years
- botulinum toxin a (except for centrally authorised products)every 3 years
- botulinum toxin type A (for centrally authorised products only)every 3 years
- bovine lung phospholipidevery 5 years
- brensocatibevery 6 months
- brentuximab vedotinevery 3 years
- brexpiprazoleevery 3 years
- brexucabtagene autoleucelevery 6 months
- brigatinibevery 3 years
- brimonidine (centrally authorised product only)every 3 years
- brimonidine (except for the centrally authorised product)every 5 years
- brimonidine / timololevery 5 years
- brinzolamideevery 5 years
- brinzolamide / brimonidine tartrateevery 5 years
- brinzolamide / timololevery 5 years
- brivaracetamevery 3 years
- brivudineevery 5 years
- brodalumabevery 3 years
- brolucizumabevery 1 year
- bromazepamevery 3 years
- bromfenacevery 5 years
- bromhexineevery 5 years
- bromocriptineevery 7 years
- bromperidolevery 5 years
- brompheniramine / caffeine / paracetamol, brompheniramine / caffeine / calcium / paracetamolevery 11 years
- brotizolamevery 3 years
- budesonide (for centrally authorised products indicated for eosinophilic esophagitis only)every 3 years
- budesonide (for centrally authorised products indicated for primary immunoglobulin A nephropathy only)every 1 year
- budesonide (nationally authorised products only)every 5 years
- budesonide / formoterolevery 5 years
- budesonide / salmeterolevery 3 years
- bulevirtideevery 1 year
- bumetanideevery 9 years
- bupivacaine (liposomal formulations)every 2 years
- bupivacaine, bupivacaine / epinephrineevery 5 years
- buprenorphine (all formulations except implants)every 4 years
- buprenorphine / naloxoneevery 4 years
- bupropionevery 5 years
- burosumabevery 3 years
- buserelinevery 5 years
- buspironeevery 3 years
- busulfanevery 3 years
- butamirateevery 10 years
- butamirate / guaifenesinevery 9 years
- butoconazoleevery 5 years
Source: European Medicines Agency, list of EU reference dates and frequency of submission of periodic safety update reports, EMA/630645/2012 Rev.165, published 21 Oct 2026.