Substances starting with H
Every substance in the newest version of the EU reference dates list that starts with H, with how often a PSUR is due. Open one for its data lock points and submission dates.
103 substances
- haemophilus influenzae / klebsiella ozaenae / klebsiella pneumoniae / moraxella catarrhalis / staphylococcus aureus / streptococcus pneumoniae / streptococcus pyogenes / streptococcus viridans vaccineevery 5 years
- haemophilus influenzae / membrane fraction of klebsiella pneumoniae / ribosomal fractions of klebsiella pneumoniae / streptococcus pneumoniae / streptococcus pyogenes vaccineevery 9 years
- haemophilus type b and meningococcal group C conjugate vaccineevery 3 years
- haemophilus type b conjugate vaccinesevery 3 years
- halometasoneevery 9 years
- halometasone / triclosanevery 9 years
- haloperidolevery 5 years
- halothaneevery 8 years
- hamamelis virginiana l. extract / phenazone / tannic acidevery 9 years
- hamamelis waterevery 13 years
- heparinevery 9 years
- heparin / zinc sulphateevery 12 years
- heparinoidevery 10 years
- heparinoid / ibuprofenevery 8 years
- hepatitis a (inactivated) / hepatitis b (rdna) vaccines (adsorbed)every 3 years
- hepatitis a (inactivated) / typhoid polysaccharide vaccine (adsorbed)every 3 years
- hepatitis A vaccines (inactivated, adsorbed)every 5 years
- hepatitis B (rDNA) vaccine (adjuvanted, adsorbed)every 3 years
- hepatitis B surface antigen, CpG 1018 adjuvantevery 3 years
- hepatitis B vaccine (rDNA)every 5 years
- herpes zoster vaccine (recombinant, adjuvanted)every 1 year
- hexamidineevery 11 years
- hexamidine / lidocaineevery 11 years
- hexaminolevulinate hydrochlorideevery 5 years
- hexetidineevery 10 years
- hexoprenaline sulfateevery 5 years
- hexylresorcinolevery 9 years
- hidrosminevery 9 years
- highly refined fish oil / glycerol / purified egg phosphatideevery 5 years
- histamine (indicated for acute myeloid leukemia)every 1 year
- horse anti-T lymphocyte immunoglobulin for human useevery 5 years
- human alfa1-proteinase inhibitor (apart from the centrally authorised product)every 5 years
- human alfa1-proteinase inhibitor (centrally authorised product)every 5 years
- human anti-d immunoglobulinevery 3 years
- human coagulation factor IXevery 5 years
- human coagulation factor VIIevery 3 years
- human coagulation factor VIII (antihemophilic factor A)every 5 years
- human coagulation factor VIII (inhibitor bypassing fraction)every 3 years
- human coagulation factor viii / human von willebrand factorevery 5 years
- human coagulation factor viii / human von willebrand factor (centrally authorised product only)every 5 years
- human coagulation factor Xevery 3 years
- human coagulation factor XIIIevery 5 years
- human fibrinogenevery 5 years
- human fibrinogen / human thrombinevery 3 years
- human heminevery 3 years
- human hepatitis B immunoglobulinevery 5 years
- human normal immunoglobulin (IgG)every 5 years
- human papillomavirus 9-valent vaccine (recombinant, adsorbed)every 3 years
- human papillomavirus vaccine (rDNA) - 2-valentevery 3 years
- human papillomavirus vaccine (rDNA) - 4-valentevery 5 years
- human plasma (pooled and treated for virus inactivation)every 3 years
- human plasma proteins with no less than 95% albuminevery 5 years
- human protein Cevery 5 years
- human prothrombin complexevery 5 years
- human rabies immunoglobulinevery 5 years
- human serum albumin (medical dilution)every 15 years
- human tetanus immunoglobulinevery 5 years
- human von willebrand factorevery 5 years
- hyaluronic acidevery 9 years
- hyaluronidaseevery 10 years
- hydralazine, dihydralazineevery 9 years
- hydrochlorothiazideevery 9 years
- hydrochlorothiazide / losartanevery 5 years
- hydrochlorothiazide / metoprololevery 8 years
- hydrochlorothiazide / nebivololevery 6 years
- hydrochlorothiazide / olmesartanevery 5 years
- hydrochlorothiazide / quinaprilevery 5 years
- hydrochlorothiazide / spironolactoneevery 5 years
- hydrochlorothiazide / telmisartan, telmisartanevery 5 years
- hydrochlorothiazide / triamterene, hydrochlorothiazide / propranolol / triamtereneevery 9 years
- hydrochlorothiazide / verapamil hydrochloride, hydrochlorothiazide / triamterene / verapamil hydrochlorideevery 9 years
- hydrochlorothiazide / zofenoprilevery 7 years
- hydrocortisone (all formulations apart from systemic use)every 5 years
- hydrocortisone (centrally authorised products for adrenal insufficiency, paediatric use only)every 3 years
- hydrocortisone (for centrally authorised products for adrenal insufficiency, congenital adrenal hyperplasia, modified-release formulations)every 3 years
- hydrocortisone (systemic formulations except for products indicated in adrenal insufficiency in a modified release tablet formulation and except for centrally authorised products for adrenal insufficiency in paediatric use only)every 5 years
- hydrocortisone / natamycin / neomycine sulphateevery 8 years
- hydrocortisone / neomycinevery 11 years
- hydrocortisone / ureaevery 9 years
- hydrocortisone acetate / lidocaine hydrochloride / mefenidramium metilsulfateevery 10 years
- hydrocortisone acetate / zinc sulfateevery 8 years
- hydrogen peroxideevery 9 years
- hydromorphoneevery 3 years
- hydroquinoneevery 8 years
- hydrotalciteevery 8 years
- hydrotalcite / simeticoneevery 9 years
- hydroxocobalamin (only for products for chemical poisoning)every 3 years
- hydroxycarbamide (except for centrally authorised product)every 3 years
- hydroxycarbamide (for centrally authorised product only)every 1 year
- hydroxychloroquineevery 5 years
- hydroxyethyl salicylate / heparin / mentholevery 9 years
- hydroxyethyl salicylate / mephenesin / methyl nicotinateevery 10 years
- hydroxyethyl starch, hydroxyethyl starch combinationsevery 1 year
- hydroxyzine, hydroxyzine combinationevery 5 years
- hyetellose / sodium chlorideevery 9 years
- hymecromoneevery 10 years
- hyoscineevery 10 years
- hyoscine butylbromideevery 9 years
- hyoscine butylbromide / metamizoleevery 10 years
- hyoscine butylbromide / paracetamolevery 8 years
- hyoscyamineevery 10 years
- hypericum perforatum L., herbaevery 5 years
- hypromelloseevery 10 years
Source: European Medicines Agency, list of EU reference dates and frequency of submission of periodic safety update reports, EMA/630645/2012 Rev.165, published 21 Oct 2026.